Lecture

Pharmacodynamics: Ligand-Receptor Binding Kinetics

Description

This lecture covers the quantitative description of ligand-receptor binding at equilibrium, including association and dissociation kinetics, the relationship between ligand concentration, binding, and effect, as well as the mechanisms of agonists, allosteric modulators, and antagonists. It also discusses the measurement and examples of association and dissociation kinetics, the impact of kon and koff rates on drug therapy, and the kinetics of effect appearance and drug washout.

About this result
This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.