Pharmacology of Pain: Mechanisms and Drug Targets

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GPCRs: Molecular Endocrinology

Explores the structure and activation of 7TM receptors and the downstream effects of CAMP and protein kinase A.

Neurological Disorders: Alzheimer's & Anxiety

Explores Alzheimer's disease, anxiety, pain, and the renin-angiotensin system, including the development of the first renin inhibitor for clinical treatment.

Cholinergic and Adrenergic Synapse

Covers the cholinergic and adrenergic synapse, effects of neurotransmitters, receptor classification, and clinical applications.

Synaptic Transmission: Electrical vs Chemical

Compares electrical and chemical synapses, emphasizing their properties and behavior, including the neuromuscular junction and synapses in the CNS.

Neurotransmitters: GABA and Glycine

Explores the classification and effects of GABA and Glycine neurotransmitters, including drug interactions.

G Protein-Coupled Receptors: Signalling Diversity and Complexity

Explores the diversity and complexity of G protein-coupled receptors, focusing on their signalling pathways, ligand effects, and cellular activity.

Pharmacology: Drug Targets and Mechanisms

Discusses ligand-receptor binding, drug targets, insulin physiology, NSAIDs, and tyrosine kinase inhibitors.

Modeling the synaptic potential

Explores the modeling of synaptic potentials and the factors influencing their amplitude.

Somatosensory System: Mechanoreceptors and Sensory Transduction

Explores the somatosensory system, focusing on mechanoreceptors and sensory transduction processes.

Pharmacodynamics: Ligand-Receptor Binding and Drug Effects

Explores ligand-receptor binding, drug effects, efficacy, potency, and biased agonism in pharmacodynamics.