Lecture

Active Model: Ion Channels & Action Potentials

Description

This lecture covers the integration of active voltage-dependent ion channels into the Hodgkin-Huxley mechanism, focusing on parameters like gnabar and gkbar which influence the density of ion channels on the membrane. By setting these parameters to non-zero values, the model starts generating action potentials. The reversal potentials of Na, K, and leak currents are explained, showcasing their roles in membrane potential changes. The impact of altering gnabar on the maximum height of action potentials is demonstrated, highlighting a critical value where the state changes. The lecture also extends the model to include a dendritic section, comparing simulations with and without dendrites to observe the effects on the model's behavior.

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