Activation and Differentiation of T Cells

This lecture covers the activation and differentiation of T lymphocytes, focusing on the process of naive T cells recognizing antigens, receiving activating stimuli, and differentiating into effector and memory cells. It explains the sequence of events in T cell responses, the signals required for T lymphocyte activation, and the role of costimulatory molecules. The lecture also discusses the functions of CD4+ and CD8+ effector T cells, the regulation of IL-2 receptor, and the therapeutic implications of costimulatory blockade. Additionally, it explores the properties and functions of memory T cells, the differentiation and functions of CD4+ effector T cells, and the major subsets of helper T cells.