Genetic Circuits: Synthetic Biology

This lecture introduces the concept of genetic circuits in synthetic biology, covering topics such as metabolic network reconstruction, metabolic engineering, and synthetic biochemistry. It explores the lac operon, enzyme systems, and the regulation of protein synthesis. The lecture delves into the design, modeling, and simulation of genetic circuits, highlighting the observations of E. coli cells' behavior when glucose and lactose are available. Special thanks are given to Adam Arkin from UC Berkeley and Ron Weiss from MIT for their course material. The lecture also discusses the lac operon mechanism, the role of IPTG in gene expression, and the construction of synthetic circuits using plasmids and vectors.