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This lecture introduces the concept of genetic circuits in synthetic biology, focusing on the lac operon as a model system. It covers the basics of genetic networks, metabolic engineering, and synthetic biochemistry. The instructor acknowledges the contributions of prominent researchers in the field. The lecture delves into the regulation of protein synthesis, the lac operon mechanism, and the use of IPTG in gene expression. It also discusses the design, modeling, and simulation of genetic circuits, emphasizing the importance of standardized biological parts. The presentation explores the construction of synthetic circuits using plasmids and vectors, highlighting the key elements required for gene expression. Additionally, it addresses the transition from natural to synthetic biology, emphasizing the design process and the biochemical reactions involved.
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