Proteostasis Regulation in C. elegans

This lecture by the instructor explores how a gonadotropin-related receptor regulates somatic proteostasis in Caenorhabditis elegans. It delves into the mechanisms of quality control machineries that monitor, recover, and remove damaged proteins, highlighting the importance of proteostasis in maintaining cellular function and preventing diseases associated with protein misfolding. The lecture also discusses the impact of aging on proteostasis, the remodeling of proteostasis early in adulthood, and the link between endocrine signaling from the germline and aging in C. elegans.