Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
Lecture
RNA Metabolism: ALS Genetics
Description
This lecture delves into the genetics of Amyotrophic Lateral Sclerosis (ALS), focusing on RNA metabolism and the role of proteins like TDP-43 and FUS/TLS. It covers mutations, oligomerization, cytosolic relocalization, stress granules, and the impact of C9orf72 hexanucleotide repeat expansion. The talk explores the formation of toxic dipeptide-repeat proteins, nucleocytoplasmic transport blockade, and potential therapeutic approaches.
Official source
About this result
This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.