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Lecture
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
This lecture covers the mechanisms of cell patterning and signalling pathways in biological development, focusing on topics such as lateral inhibition, equivalence groups, and the Notch signalling pathway. It discusses the role of various pathways like Receptor Tyrosine Kinase and Delta-Notch in cell differentiation and pattern formation, using examples from C. elegans and Drosophila. The lecture also explores the concept of global inhibitory signals and the interplay between induction and inhibition in determining cell fate. Additionally, it delves into the genetic basis of equivalence group commitment and the impact of mutations on cell development.