Lecture

Total Synthesis: Regidins and Ecteinascidin-743

In course

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Description

This lecture covers the total synthesis of Regidins and Ecteinascidin-743, detailing a three-step synthesis process with high yields and the deep insight into the structure provided by Ugi 4CR. It also explores Fukuyama's synthesis of Ecteinascidin-743 and the unique structure of (+)-Peganumine A, an octacyclic alkaloid with low uM activity against various cancer cell lines.

Instructor

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Official source

https://mediaspace.epfl.ch/media/0_6kpujxyv

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Ontological neighbourhood

Health sciences

Pharmacology: Drug discovery

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