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This lecture covers the components of the cellular cytoskeleton, including actin filaments, intermediate filaments, microtubules, and plasma membrane-associated cytoskeleton. It explains the structure, function, and dynamics of these components, highlighting their roles in muscle contraction, cell crawling, and surface movement. The lecture also discusses solvent-free molecular dynamics simulations, Brownian dynamics, and Brownian dynamics simulations of filament growth. It explores the use of Monte Carlo simulations to study systems with larger units and the importance of detailed balance in Metropolis Monte Carlo simulations.