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This lecture covers the structure and function of transitional epithelium, focusing on the urinary system. It explains the histological features of the ureter, bladder, and urethra, detailing the changes in epithelial cells when the bladder is empty or full. The discussion includes the controversy over whether transitional epithelium is stratified or pseudostratified, and the role of tensional forces in shaping the epithelial cells. Additionally, it explores the composition of urothelium, the impermeability of salts and water, and the presence of uroplakins. The lecture also delves into the cellular components of transitional epithelium, such as superficial and basal cells, and the significance of plaques in the epithelial lining.