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This lecture covers the process of brain development, including neurodevelopment, neurulation, and the formation of major brain subdivisions. It delves into the role of morphogens in inducing neural plate formation, the establishment of cell identity, and the formation of the cerebral cortex. The lecture also explores adult neurogenesis, from early evidence in rats to recent studies in humans, highlighting the influence of environmental factors on neurogenesis. Additionally, it discusses the impact of neurogenesis on hippocampal memory circuits and its potential role in depression and brain injury recovery.