Lecture

BiP-mediated ER quality control: assists and hurdles

Description

This lecture explores the BiP-mediated ER quality control process, focusing on distinguishing nascent unfolded proteins from misfolded ones, targeting proteins for degradation, and assisting in proper folding. Unique challenges in B cell development are discussed, along with the role of chaperones in cellular and protein homeostasis.

Official source

https://mediaspace.epfl.ch/media/0_97tv9kk5

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Ontological neighbourhood

Biology

Cell biology: Membrane biology

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