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Lecture
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
This lecture delves into the development of a new approach for high-speed observations of proteins, focusing on large-amplitude domain motions, fast backbone motions, side chain motions, catalysis, protein folding, substrate binding, and allosteric regulation. It explores time-resolved methods offering atomic resolution, cryo-electron microscopy, in-situ melting and revitrification, real-time observation of rapid melting, and proof of principle experiments. The lecture also covers temperature control, capsid dynamics of CCMV, and future outlooks in the field of cryo-EM imaging.