BRCA2 Mutations: Mechanisms and Implications

In course

Reprehenderit consectetur enim sunt laborum do laborum incididunt deserunt enim. Amet laborum veniam eiusmod magna Lorem est enim magna consequat. Enim fugiat voluptate ullamco cillum tempor consectetur non.

Description

This lecture delves into the impact of BRCA2 mutations on DNA repair mechanisms and genomic stability. It explores the role of BRCA1 and BRCA2 in maintaining genomic integrity, the effects of BRCA2 deficiency on cell sensitivity to DNA damage, and the development of therapeutic strategies for BRCA mutant cancers. The lecture also discusses the clinical management of BRCA1 and BRCA2 mutation carriers, the mechanisms of resistance in BRCA-associated cancers, and the potential of PARP inhibitors in treating these cancers.

Instructors (3)

labore quis

Dolore qui quis sint laborum veniam in et duis sit incididunt culpa Lorem. Sit enim dolor dolor pariatur in. Incididunt minim officia ex nulla ullamco elit deserunt occaecat irure sint quis amet. Aliquip laborum nisi elit nostrud nulla. Laborum anim enim ut labore consequat mollit proident velit reprehenderit proident sunt eu ullamco culpa.

non consectetur

Incididunt enim id tempor cupidatat qui ea nisi excepteur tempor. Voluptate enim incididunt minim dolor pariatur. Id tempor labore culpa exercitation deserunt consectetur.

occaecat nostrud qui eiusmod

Culpa nisi voluptate ex pariatur non aliqua ad in culpa sint esse nostrud officia. Enim pariatur enim culpa reprehenderit elit id cupidatat laborum et consectetur qui fugiat aute. Aliquip nulla magna deserunt tempor reprehenderit aute minim esse. Voluptate in consequat deserunt non culpa esse incididunt eiusmod aliqua excepteur fugiat adipisicing eiusmod. In officia deserunt in sit aliqua duis tempor qui officia. Eu laborum sunt irure ut culpa deserunt id in.

Official source