Solid-state NMR and Quadrupoles

This lecture covers the principles of solid-state NMR, focusing on the unique aspects of solid samples compared to liquids. It explains the anisotropic nature of chemical shifts in solids and how rapid molecular motion affects NMR spectra. The lecture delves into the quadrupolar interaction in nuclei with spins greater than 1/2, detailing the Hamiltonian and its impact on spectral features. It also explores techniques like magic angle spinning to regain high resolution in solid-state NMR. Applications in studying complex structures like cyclosporin A and silver acetate are discussed, highlighting the sensitivity of chemical shift anisotropy to electronic structure.