DNA Analysis: Trisomy Detection and Paternity Testing

This lecture covers the analysis of DNA, focusing on the detection of trisomy 21 (Down's syndrome) using microsatellites. It explains how DNA profiles are established, the role of non-coding DNA, and the applications of microsatellite analysis in determining parental origin and paternity. The lecture also delves into the probabilistic calculations required for paternity testing and the genetic variations in gametes. It concludes with real-life examples illustrating the use of microsatellites in identifying individuals and excluding paternity.