Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
This lecture covers the fundamentals of epigenomics, focusing on DNA methylation and histone modifications. It explains the role of epigenetic codes in gene expression, the process of bisulfite sequencing to detect DNA methylation, and the significance of histone modifications in chromatin accessibility. The lecture also discusses the impact of epigenetic dysregulation in diseases like Alzheimer's. Additionally, it explores techniques like chromatin immunoprecipitation and Hi-C for studying chromatin interactions and epigenetic changes.