Epigenomics: DNA Methylation and Histone Modifications

Description

This lecture covers the fundamentals of epigenomics, focusing on DNA methylation and histone modifications. It explains the role of epigenetic codes in gene expression, the process of bisulfite sequencing to detect DNA methylation, and the significance of histone modifications in chromatin accessibility. The lecture also discusses the impact of epigenetic dysregulation in diseases like Alzheimer's. Additionally, it explores techniques like chromatin immunoprecipitation and Hi-C for studying chromatin interactions and epigenetic changes.

In MOOCs (6)

Instructor

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Official source

https://mediaspace.epfl.ch/media/0_axxila4q

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Ontological neighbourhood

Biology

Genetics: Molecular genetics

Cell biology: Cell cycle

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