Lecture
This lecture explores neuroepigenetics, focusing on chromatin structure and inheritance. It covers the levels of investigation in neurodegenerative disorders, including population and individual perspectives, epigenetic dysregulation in Alzheimer's disease, histone modifications, nucleosome structure, and the dynamic nature of chromatin. The lecture delves into the impact of DNA methylation and histone post-translational modifications on gene transcription, as well as the intergenerational and transgenerational effects of epigenetic changes induced by environmental factors.