Mannich Reaction: Applications and Mechanism

In course

Incididunt cupidatat duis consequat labore laboris magna consequat quis. Nostrud aute anim aliqua labore ut non. Duis tempor aute magna veniam sit occaecat eu ipsum.

Description

This lecture covers the Mannich reaction, focusing on the generation of imines and its application in natural product synthesis, such as Robinson's Three-Component Synthesis of Tropinone. It also discusses the mechanism of the Mannich reaction, including the formation of iminium and Eschenmoser's salt. Furthermore, it explores related reactions like Knoevenagel condensation, Michael addition, and Weiss-Cook condensation. The lecture concludes with the Robinson Annulation, showcasing the combination of Michael addition and intramolecular aldolization.

Instructor

eiusmod eiusmod

Laborum do enim occaecat ex exercitation minim ad reprehenderit consequat ut. Magna ipsum consequat occaecat Lorem enim qui anim fugiat dolor reprehenderit aute. Cupidatat nisi aliquip commodo officia. Et tempor amet sit proident minim proident officia. In laboris velit velit id magna.

Official source

https://mediaspace.epfl.ch/media/0_bf71d1n8

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Related lectures (32)