Surfaces: Biomaterials and Surface Interactions

This lecture covers the introduction to biomaterials, including naturally derived and manmade biomaterials, polymers, nanoparticles, and surfaces. It explores the challenges faced by biomaterial surfaces, the foreign body response, protein fundamentals, and interactions with surfaces. The importance of location for biomaterials inside and outside the body is discussed, along with surface modifications, wear resistance, and biocompatibility. The lecture also delves into the foreign body response, matrix deposition, fibrous encapsulation, and interactions of proteins with surfaces, highlighting the impact on both proteins and materials. Various protein structures, chemical functionalities, and interactions with surfaces are explained, emphasizing the implications for material engineering and immune responses.