C-N Coupling with Biarylphosphine Ligands

This lecture covers the mechanisms and applications of C-N coupling reactions using biarylphosphine ligands. It discusses the effects of different ligands on the reaction scope, the importance of steric and electronic properties, and the proposed mechanisms via DFT studies. The lecture also explores the use of these ligands in pharmaceutical synthesis and the challenges and solutions encountered in C-O coupling reactions with Pd complexes.