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This lecture discusses the development of superparamagnetic nanoparticles for high-resolution MRI detection of lymph node metastases in prostate cancer. It covers the targeted treatment of metastases through hyperthermia, the specific adsorption of nanoparticles for MRI contrast imaging, in-vivo behavior studies, and the development of software for treatment planning. The lecture also explores the functionalization of nanoparticles with targeting molecules, in vivo tumor models, simulation platforms for treatment planning, and the future steps for animal testing and product development.