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This lecture covers the environmental significance of the sulfur and nitrogen cycles, including the use of wetlands to treat AMD waters, bioleaching in abandoned mines, and the diversity of sulfur and sulfate reducing bacteria. It also explores the processes of nitrogen fixation, denitrification, nitrification, and anammox, highlighting the key enzymes and organisms involved. The lecture delves into the complex interplay of microbial processes that transfer nitrogen between different oxidation states, emphasizing the critical role of microbes in maintaining nitrogen levels in various environments.