Neocortical inhibition: cellular mechanisms

This lecture covers the cellular mechanisms of neocortical inhibition, focusing on different types of GABAergic neurons such as fast-spiking, parvalbumin-expressing cells, somatostatin-expressing neurons, VIP-expressing neurons, and neurogliaform cells. It explains how these neurons innervate and inhibit excitatory pyramidal neurons through various mechanisms, including proximal and distal dendritic inhibition, dis-inhibition, and volume transmission. The lecture also discusses the role of GABAergic neurons in regulating synaptic input and maintaining the balance of excitation and inhibition in the neocortex.