SERF-related proteins functions in amyloid acceleration and G-quadruplex binding

This lecture by the instructor James Bardwell explores the functions of SERF-related proteins in accelerating amyloid formation and binding to G-quadruplex structures. The lecture covers topics such as the role of SERF in amyloid aggregation, its impact on amyloid kinetics, and its interaction with amyloid-prone proteins. Additionally, it delves into the structural diversity of SERF proteins, their classification, and their binding affinity to DNA and RNA G-quadruplexes. The lecture also discusses the use of Ion Mobility Mass Spectrometry to study SERF proteins and their complexes. Overall, the lecture provides insights into the complex mechanisms underlying SERF-related proteins' involvement in amyloid formation and G-quadruplex binding.