Genetic Inheritance Beyond Mendel

This lecture explores genetic inheritance beyond Mendel's laws, covering concepts such as incomplete dominance, codominance, multiple alleles, lethal alleles, and epistasis. It delves into examples like ABO blood groups, the Bombay phenotype, and the impact of multiple genes on phenotypes. The discussion extends to genic and epistatic interactions, including dominant and recessive epistasis, and their effects on phenotypic ratios. Furthermore, it examines pleiotropy, using Marfan syndrome as an example, and gene-environment interactions, discussing penetrance, expressivity, and factors influencing variable expressivity like temperature and nutrition.