Disentangling Confounding and Nonsense Associations

Description

This lecture discusses the conflation of statistical dependence with confounding, highlighting methods that fail to control for general forms of confounding. It covers topics such as nonsense associations, confounding due to dependence, and general confounding. The lecture also explores causal inference with multiple treatments and unmeasured confounding, emphasizing the distinction between existing methods and new, improved approaches. Additionally, it delves into confounding by dependence, network simulations, and the implications of confounding in various fields. The instructor presents recent methods to control for unmeasured confounding, the limitations of orthogonalization methods, and the development of novel semiparametric causal inference methods.

Official source

https://mediaspace.epfl.ch/media/0_ht0oopl9

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Related lectures (3)

Related concepts (107)

Confounding

In causal inference, a confounder (also confounding variable, confounding factor, extraneous determinant or lurking variable) is a variable that influences both the dependent variable and independent variable, causing a spurious association. Confounding is a causal concept, and as such, cannot be described in terms of correlations or associations. The existence of confounders is an important quantitative explanation why correlation does not imply causation.

Causal model

In the philosophy of science, a causal model (or structural causal model) is a conceptual model that describes the causal mechanisms of a system. Several types of causal notation may be used in the development of a causal model. Causal models can improve study designs by providing clear rules for deciding which independent variables need to be included/controlled for. They can allow some questions to be answered from existing observational data without the need for an interventional study such as a randomized controlled trial.

Propensity score matching

In the statistical analysis of observational data, propensity score matching (PSM) is a statistical matching technique that attempts to estimate the effect of a treatment, policy, or other intervention by accounting for the covariates that predict receiving the treatment. PSM attempts to reduce the bias due to confounding variables that could be found in an estimate of the treatment effect obtained from simply comparing outcomes among units that received the treatment versus those that did not. Paul R.

Causal inference

Causal inference is the process of determining the independent, actual effect of a particular phenomenon that is a component of a larger system. The main difference between causal inference and inference of association is that causal inference analyzes the response of an effect variable when a cause of the effect variable is changed. The science of why things occur is called etiology, and can be described using the language of scientific causal notation. Causal inference is said to provide the evidence of causality theorized by causal reasoning.

Scientific control

Informal improvements in any process or enquiry have been made by comparison between what was done previously and the new method for thousands of years. A scientific control is a modern formal experiment or observation designed to minimize the effects of variables other than the independent variable (i.e. confounding variables). This increases the reliability of the results, often through a comparison between control measurements and the other measurements. Scientific controls are a part of the scientific method.