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This lecture explores the journey of Prof. Daniel Thalmann, from his interest in virtuality at a young age to his groundbreaking work in creating virtual humans. It delves into the development of immersive VR systems, the challenges of controlling digital facsimiles, and the applications of embodied and intelligent virtual agents in various fields, including medicine. The lecture also discusses the introduction of virtual or synthetic vision and its impact on behavioral animation. Overall, it provides a comprehensive overview of the evolution and applications of virtual humans and related technologies.