Alkane Chlorination: Selectivity and Reactivity

This lecture covers the chlorination of alkanes, focusing on the selectivity and reactivity of different types of hydrogen atoms. The instructor explains the radical mechanism involved in the chlorination process, highlighting the relative reactivity of primary and secondary hydrogen atoms. Various examples, such as the chlorination of ethane and propane, are used to illustrate the concepts. The lecture also discusses the impact of chlorine selectivity on the abstraction of hydrogen atoms. Additionally, the presentation delves into the challenges and alternatives to radical chlorination, including the use of other less toxic sources like N-chloro-succinimide. Overall, the lecture provides insights into the fundamental principles of alkane chlorination reactions.