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Lecture
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
This lecture covers the analysis of genotypes and variants information extracted from openSNP data, focusing on conducting a Genome-Wide Association Study (GWAS) to explore the association between genetic variants and phenotypes like height. The lecture includes data exploration, statistical methods to assess the impact of covariates on phenotypes, linear regression modeling, and visualization techniques such as Manhattan plots. Students will learn how to run GWAS with and without covariates, interpret p-values, compare results, and conduct meta-analysis with the GIANT Study data.