Mutations and Genetic Variability

This lecture covers the molecular basis of alleles, exploring different types of mutations such as loss-of-function and gain-of-function mutations, as well as conditional mutations. It also delves into the effects of mutations on phenotype, exemplified by the Himalayan rabbit and Siamese cat. The lecture further discusses the impact of the environment on phenotype, illustrated by examples like the Hydrangea plant and the gecko. Additionally, it explains the process of meiosis, highlighting the differences between meiosis and mitosis, and the significance of genetic shuffling and homologous recombination. The lecture concludes with a detailed explanation of chromosomal abnormalities, including aneuploidy and chromosomal mosaicism.