This lecture covers conventional non-invasive brain stimulation techniques such as Transcranial Magnetic Resonance (TMS) and Transcranial Electric Stimulation (tES), including Bidocal tES and Multifocal tES. It discusses the diagnostic and therapeutic applications of techniques like tDCS, tACS, and tRNS, highlighting their effects on brain activity modulation. The lecture also explores the mechanisms behind ultrasound neuromodulation, focusing on the effects of sound waves on nerve fibers and muscle tissues. It delves into the safety challenges and parameters involved in ultrasound neuromodulation, emphasizing the importance of targeting specific brain regions and ensuring safety protocols.