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This lecture covers the functional anatomy and biomechanics of the musculoskeletal system, focusing on pathologies related to biomechanical aspects. The course aims to widen students' competences in a multidisciplinary field, provide theoretical bases for biomechanical models, and demonstrate how an engineering approach can offer new insights in medical and biological aspects. Topics include biomechanics at the body, tissue, and clinical levels, with a study plan tailored for master students in various engineering sections. The lecture also delves into mini-projects where students work on biomechanical analyses, design, and presentations under the guidance of medical and engineering advisors.