Dynamic Nuclear Polarization: Fundamentals

This lecture introduces the concept of Dynamic Nuclear Polarization (DNP) in magnetic resonance, focusing on enhancing signal-to-noise ratio in liquid-state NMR. Topics include the basic steps of DNP, the use of polarizing agents like [1-13C] Sodium Pyruvate, and the impact of natural abundance on sensitivity. The lecture also covers the theoretical framework behind DNP, the role of electron polarization, and the requirements for achieving optimal polarization. Additionally, it discusses the contributions of key figures like Albert W. Overhauser and the potential applications of DNP in improving NMR sensitivity.