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Explores Chemical Biology's interdisciplinary nature, enzyme inhibition, genetic methods, and metabolic regulation, highlighting its real-world relevance through recent Nobel Prize contributions.
Explores quantitative proteome profiling for drug target identification through activity-based protein profiling and advanced mass spectrometry techniques.
Explores small molecule drugs for infectious diseases, covering global mortality rates, viral and bacterial injuries, antiviral and antibacterial agents, and the development of COX2 inhibitors.
Explores kinase inhibitors, enzyme inhibition methods, transition state analog drugs, and the significance of covalent drugs in pharmaceutical research.
Covers enzyme inhibition mechanisms, drug modes of action, targeted protein degradation using PROTACs, and the bump-hole method for protein-ligand engineering.
