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This lecture introduces the field of energy systems engineering, focusing on methods to make informed decisions in designing process and energy systems. The instructor, François Maréchal, shares his expertise in process integration and energy usage analysis. The course covers topics such as energy transition, carbon dioxide mitigation, and maximizing profit while minimizing costs. Students will work on a project involving a dairy company, exploring options like producing Rivella, biogas, and carbon dioxide capture. The course emphasizes computational thinking, using software tools for analysis, generation, interpretation, and reporting of data. The industry's role in energy consumption, efficiency improvement, and climate change mitigation is highlighted, with a focus on industrial symbiosis and the need for increased efficiency to meet emission reduction targets.