Gene Regulation: Transcription Mechanisms and Networks

This lecture covers the vital role of gene regulation in controlling the synthesis of functional products in cells, essential for cellular differentiation and organism adaptability. It explains the mechanisms of transcription regulation, including chromatin accessibility, DNA looping, and epigenetic modifications, as well as the involvement of transcription factors, promoters, and gene regulatory networks. The lecture also delves into the concepts of activators, repressors, combinatorial regulation, and feedback loops during transcription, highlighting the interplay between different elements in the regulation process, such as enhancer sequences, silencer elements, and RNA processing.