This lecture covers the fundamental concepts of probability and statistics, addressing questions such as the likelihood of events, the deviation in coin tosses, and the trajectory of particles. It delves into the difference between probability and statistics, explaining how they relate to models and data. The lecture also explores the application of statistics in real-life scenarios, such as estimating proportions and testing hypotheses. Additionally, it discusses the detection of particles at the CMS experiment and the Standard Model of Elementary Particles, including the discovery of the top quark. Various resources and books for further study in probability and statistics are recommended.