Prader-Villy Syndrome: Genetic Mechanisms and Clinical Implications

This lecture delves into the genetic mechanisms underlying Prader-Villy syndrome, comparing it with Angelman syndrome. The instructor discusses the molecular basis of the disorders, including DNA methylation patterns and chromosomal abnormalities. The lecture covers topics such as uniparental disomy, point mutations, and the impact of parental age on genetic disorders. Through detailed explanations and examples, the instructor highlights the importance of understanding these genetic conditions for diagnosis and management.