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Lecture
Inhibitor Design & Analysis
Description
This lecture covers the fundamentals of inhibitor design and analysis, focusing on the modes of action of reversible and irreversible drugs, developing chemical intuition for target engagement, and the importance of targeting cysteine residues. It also discusses the concepts of covalent vs. non-covalent parameters in successful drug development, with a special emphasis on the role of protein cysteines in drug resistance.
Official source
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