Cell Traps: Microfluidic Devices and Arrays

This lecture covers the use of microfluidic devices for trapping single cells, focusing on the interest of single cell studies for understanding population variability and sub-populations. Various technologies such as chemical surface patterning, mechanical positioning, and dielectrophoretic forces are discussed. The lecture also explores cell arrays with micro-wells, hanging drop arrays for cell aggregates, linear trap arrays for single cells, and trapping arrays for cell pairs. Additionally, it delves into immunocapture by posts arrays, a 'herringbone' cell capture device, CTC trapping by size, and rolling cells for measuring cell-cell mechanical interactions.