Extracellular Matrix: Structure, Function, and Proteins

This lecture covers the extracellular matrix (ECM), including collagen, fibronectin, laminin, and proteoglycans. It explains how the ECM is made and remodeled by cells, its role in regulating cell function, and the unique features of different tissues. The lecture also delves into adhesive proteins like integrins, collagen receptors, and laminin receptors, detailing their functions and activation states. Furthermore, it explores the mechanical properties of the ECM, such as elasticity and stiffness, and the implications of the ECM in tissue differentiation, growth, and response to injury.