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This lecture explores the challenges and perspectives of data privacy in eHealth research, focusing on the University of Applied Sciences and Arts Western Switzerland. It covers topics such as data privacy issues, projects in eHealth research, and the use of personal data in medical contexts. The lecture delves into the importance of GDPR compliance, the management of sensitive health data, and the principles of data handling. It also discusses the role of decentralized agents in ensuring data autonomy and the semantic representation of interactions. The presentation concludes with a vision for decentralized personal data privacy interactions and outlines future work in developing domain-specific vocabularies and multi-agent environments.