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This lecture covers the theory and practical aspects of oxidation and disinfection in water treatment. It explains the settling behavior of particles, the theory of discrete settling, calculation of drag coefficient, critical settling velocity, and overflow rate in sedimentation tanks. It also discusses filtration processes, including slow sand filters and rapid filtration. The lecture delves into the application of chemical oxidants like chlorine, chlorine dioxide, and ozone in water treatment, their role in disinfection, and removal of micropollutants. It explores the history of chlorination, forms of chlorine addition, speciation of aqueous chlorine, and reactions of chlorine in water. Additionally, it touches on the importance of water quality in chlorination processes and introduces ozone as an alternative oxidant in water treatment.