Lecture

Fine-grained Patterning: Lateral Inhibition

Description

This lecture covers the development of the vulva in C. elegans, focusing on signal transduction pathways, intracellular signaling proteins, and the role of Lin-3, Let-23, and Lin-12 in inducing and inhibiting target gene expression. It also discusses the Notch signaling pathway, equivalence group ablation, and the global inhibitory signal revealed by Lin-15. The lecture delves into the mechanisms of induction, lateral inhibition, and neuronal precursor specification, highlighting the interplay between these processes in pattern formation.

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