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This lecture by the instructor presents the IR Sense project, focusing on an integrated sensing platform for gases and liquids using infrared spectroscopy. The lecture covers the development of optical technologies for low-cost sensors, the application of optical sensing for measuring small molecules, and the specific examples of carbon dioxide isotopic ratio measurement and cocaine detection in saliva. The lecture also discusses the design of a gas sensor based on optics, including the use of quantum cascade laser and detector, as well as the development of a waveguide for liquid measurements. The results show promising accuracy in isotope ratio measurements and the detection of cocaine in liquids, with potential for commercialization and future expansion to multi-gas detection systems.