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This lecture covers the construction of the human genetic linkage map, starting with the identification of markers and their sequencing. It explains the process of finding linked markers and determining their order, using genomes from well-characterized organisms as guides. The lecture also delves into the concept of genetic map units and the recombination frequency along chromosomes. It discusses the variation in recombination rates across organisms and the implications of this variation. Additionally, it explores the size of the human genome in comparison to other sequenced genomes, highlighting the complexity and diversity of genetic information.