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This lecture covers public attitudes towards animal research, ethical perspectives defending animal welfare and rights, the Swiss regulatory framework emphasizing the dignity of animals, the 3Rs principle, animal rights activism, and the case of primate research. It also discusses different views on the acceptability of animal research, the types of animals considered acceptable for research, animal welfare from a pathocentric approach, and animal rights from a deontological approach. The debate between abolition and regulation in animal rights is also addressed, along with the concept of New Welfarism.